Antivirals

  • Acyclovir

Acyclovir

  • Mechanism of Action: Antiviral; inhibits DNA polymerase
  • Indications: Commonly used to treat oral/genital herpes, varicella, zoster (shingles), and VZV encephalitis.
  • Contraindications: allergy to class/drug
  • Dosage: depends on condition; common dosage is 800mg PO 5x/day x 7 days.
  • Half-life: 2.5 – 3.3 hours
  • Adverse Reactions: Common side effects include N/V, headache, and rash. Serious reactions include hallucinations/psychosis
  • Special Considerations: N/A
Video Credit: USMLE Pass

*Deep Dive: Acyclovir (WikEM)


Brandon Simpson, PA-C
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