Antivirals

Rapid Review

• Mechanism of Action: Antiviral; inhibits DNA polymerase
• Indications: Commonly used to treat oral/genital herpes, varicella, zoster (shingles), and VZV encephalitis.
• Contraindications: allergy to class/drug
• Dosage: depends on condition; common dosage is 800mg PO 5x/day x 7 days.
• Half-life: 2.5 – 3.3 hours
• Adverse Reactions: Common side effects include N/V, headache, and rash. Serious reactions include hallucinations/psychosis
• Special Considerations: N/A

Pearls

Deep Dive

• Acyclovir (WikEM)