Corticosteroids


Dexamethasone

Rapid Review

  • Mechanism of Action: Corticosteroid; decreases production of inflammatory mediators, reverses capillary permeability, and suppresses normal immune response.
  • Indications: Allergic reactions, asthma, and autoimmune conditions. May also be used to treat acute COVID-19 infections. 
  • Contraindications: allergy to drug or class
  • Dosage: Usually 4 – 20mg in single or divided doses; depending on disease.
  • Half-life: 4 hours for oral, 1-5 hours for IV
  • Adverse Reactions: nausea, dizziness, 
  • Special Considerations: Use may have small increase in risk for sepsis, fractures, and venous thromboembolism

Pearls

Video Credit: Concept Clear


Hydrocortisone

Rapid Review

Pearls

Deep Dive



Methylprednisolone

Rapid Review

Pearls

Deep Dive



Prednisone

Rapid Review

Pearls

Deep Dive

Brandon Simpson, PA-C
Latest posts by Brandon Simpson, PA-C (see all)
  • Blog - 25 Feb 2021