Dermatological


Atopic Dermatitis

Rapid Review

  • Background
    • Atopic dermatitis is a chronic relapsing inflammatory skin disorder with a complex pathogenesis involving genetic susceptibility, immunologic and epidermal barrier dysfunction, and environmental factors. 
  • Signs/Symptoms
    • Itchy/scaly rash, particularly on cheeks/trunk and flexor surfaces. Pruritus is the primary symptom.
  • Diagnosis
    • Clinical diagnosis
  • Treatment
    • Identify and eliminate triggers. Topical steroid (hydrocortisone, triamcinolone, etc.). Emollients (Vaseline, Aquaphor) can be used on top of steroids.

Pearls

Credit: JJ Medicine


Cellulitis

Rapid Review

  • Background
    • Cellulitis is an infection of the soft tissue beneath the skin, most commonly caused by bacteria that normally colonize the skin surface (ex. Staph aureus).
  • Signs/Symptoms
    • Tender, warm, erythematous rash with poorly demarcated borders. May have an associated skin abscess. Patients may also experience fever/chills, malaise, or headache.
  • Diagnosis 
    • Clinical diagnosis; ultrasound may aid in the diagnosis by showing a “cobblestone appearance” and identifying potential abscesses 
  • Treatment
    • Cephalexin or amoxicillin for simple cellulitis. For suspected MRSA, use TMP/SMX, clindamycin, or doxycycline.

Pearls

Video Credit: Zero To Finals


Contact Dermatitis

Rapid Review

  • Background
    • Contact dermatitis is inflammation of the skin caused by direct contact with irritants (irritant contact dermatitis) or allergens (allergic contact dermatitis). 
  • Sign/Symptoms
    • Well-demarcated erythematous rash on site of contact, with possible vesicles or erosions. Rash will typically be pruritic.
  • Diagnosis
    • Clinical diagnosis based on history, exam, and exposure history. Allergists/dermatologists may use patch test to determine precise cause.
  • Treatment
    • Removal of irritant/allergen, topical steroids (hydrocortisone, triamcinolone), and emollients. 

Pearls

Video Credit: Medicosis


Necrotizing Fasciitis

Rapid Review

  • Background
    • Necrotizing fasciitis is a severe bacterial infection that can lead to tissue destruction, systemic infection and death. It is sometimes referred to as “flesh eating bacteria”. It is typically caused by a mix of bacteria that release a toxin which destroys surrounding tissue.
  • Signs/Symptoms
    • Pain out of proportion to exam. Erythema, swelling/edema, hemorrhagic bullae, lymphadenopathy
  • Diagnosis
    • Ultrasound may show thickened fascia planes. CT is the study of choice, however, surgical exploration is the only definitive method of diagnosing necrotizing fasciitis.
  • Treatment
    • Treat initially with broad-spectrum antibiotic coverage (Piperacillin-Tazobactam + Clindamycin + Vancomycin). Surgical debridement required for definitive treatment.

Pearls

Video Credit: EM in 5


Steven Johnson Syndrome

Rapid Review

  • Background
    • Steven-Johnson Syndrome (SJS) is a severe skin and mucous membrane reaction that causes necrosis and sloughing of the epidermis (top layer of skin). The most common cause is medications, but can also occur due to infection and in many cases the cause is not known. When skin sloughing involves greater than 30% of the body surface, the term toxic epidermal necrolysis (TEN) is used.
  • Signs/Symptoms
    • Vesicles and bullae involving < 10% of the body on at least 2 mucosal sites. Patients often experience a prodrome (fever, URI symptoms, headache, and malaise)
  • Diagnosis
    • Clinical diagnosis
  • Treatment
    • Removal of cause (usually medications), fluid resuscitation, referral to burn center

Pearls

Video Credit: Medcrine

Brandon Simpson, PA-C
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  • Blog - 25 Feb 2021